“In an account both lyrical and capacious, Mukherjee takes us through an evolution of human understanding: from the seventeenth-century discovery that humans are made up of cells to our cutting-edge technologies for manipulating and deploying cells for therapeutic purposes” ( The New Yorker).

Told in six parts, and laced with Mukherjee’s own experience as a researcher, a doctor, and a prolific reader, The Song of the Cell is both panoramic and intimate-a masterpiece on what it means to be human. And all could be perceived as loci of cellular therapies.įilled with writing so vivid, lucid, and suspenseful that complex science becomes thrilling, The Song of the Cell tells the story of how scientists discovered cells, began to understand them, and are now using that knowledge to create new humans. A hip fracture, a cardiac arrest, Alzheimer’s dementia, AIDS, pneumonia, lung cancer, kidney failure, arthritis, COVID pneumonia-all could be reconceived as the results of cells, or systems of cells, functioning abnormally. The discovery of cells-and the reframing of the human body as a cellular ecosystem-announced the birth of a new kind of medicine based on the therapeutic manipulations of cells. Our organs, our physiology, our selves-hearts, blood, brains-are built from these compartments. It was the fact that complex living organisms are assemblages of tiny, self-contained, self-regulating units. What they saw introduced a radical concept that swept through biology and medicine, touching virtually every aspect of the two sciences, and altering both forever.

Mukherjee begins this magnificent story in the late 1600s, when a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek looked down their handmade microscopes. In The Song of the Cell, the extraordinary author of the Pulitzer Prize-winning The Emperor of All Maladies and the #1 New York Times bestseller The Gene “blends cutting-edge research, impeccable scholarship, intrepid reporting, and gorgeous prose into an encyclopedic study that reads like a literary page-turner” ( Oprah Daily). Named a New York Times Notable Book and a Best Book of the Year by The Economist, Oprah Daily, BookPage, Book Riot, the New York Public Library, and more! Winner of the 2023 PROSE Award for Excellence in Biological and Life Sciences!

The gene siddhartha mukherjee review